Peb siv cov ncuav qab zib los txhim kho koj qhov kev paub.Los ntawm txuas ntxiv mus saib lub vev xaib no, koj pom zoo rau peb siv cov ncuav qab zib.Xav paub ntxiv.
Muaj qhov xav tau ceev nrooj rau cov ntaub ntawv tshawb fawb biomedical ntawm cov tsiaj txhu kom ua tau zoo dua qub thiab nthuav dav, thiab kom tswj tau zoo dua thiab ntsuas cov xwm txheej ib puag ncig ntawm cov kab lis kev cai ntawm tes.Qhov no yuav ua rau cov qauv ntawm tib neeg lub cev muaj zog ntau dua thiab ua rau muaj kev rov tsim dua tshiab ntawm kev tshawb fawb.
Ib pab pawg ntawm KAUST cov kws tshawb fawb thiab cov npoj yaig hauv Saudi Arabia thiab Tebchaws Meskas tau tshuaj xyuas 810 cov ntawv xaiv xaiv ntawm cov kab mob ntawm tes.Tsawg dua 700 ntawm lawv koom nrog 1,749 kev sim kab lis kev cai ntawm tus kheej, suav nrog cov ntaub ntawv cuam tshuam ntawm ib puag ncig ntawm kab lis kev cai nruab nrab ntawm tes.Pab neeg tshawb xyuas qhia tau tias yuav tsum tau ua haujlwm ntau ntxiv los txhim kho qhov cuam tshuam thiab rov tsim dua ntawm cov kev tshawb fawb no.
Cultivate hlwb nyob rau hauv lub incubator tswj raws li tus txheej txheem raws tu qauv.Tab sis cov hlwb yuav loj hlob thiab "ua pa" nyob rau lub sijhawm, sib pauv roj nrog ib puag ncig ib puag ncig.Qhov no yuav cuam tshuam rau thaj chaw hauv cheeb tsam uas lawv loj hlob, thiab tej zaum yuav hloov cov kab lis kev cai acidity, yaj oxygen, thiab cov pa roj carbon dioxide.Cov kev hloov pauv no cuam tshuam rau kev ua haujlwm ntawm tes thiab tuaj yeem ua rau lub cev txawv txav ntawm cov xwm txheej hauv tib neeg lub cev.
Klein tau hais tias "Peb qhov kev tshawb fawb qhia txog qhov uas cov kws tshawb fawb tsis quav ntsej saib xyuas thiab tswj hwm lub cellular ib puag ncig, thiab qhov twg cov ntawv ceeb toom ua rau lawv ncav cuag kev tshawb fawb los ntawm cov txheej txheem tshwj xeeb," Klein tau hais.
Piv txwv li, cov kws tshawb fawb pom tau tias kwv yees li ib nrab ntawm cov ntawv txheeb xyuas tsis tau tshaj tawm qhov kub thiab txias thiab carbon dioxide teeb tsa ntawm lawv cov kab lis kev cai ntawm tes.Tsawg dua 10% tshaj tawm cov ntsiab lus atmospheric oxygen nyob rau hauv lub incubator, thiab tsawg dua 0.01% qhia cov acidity ntawm nruab nrab.Tsis muaj cov ntaub ntawv tshaj tawm txog cov pa oxygen lossis carbon dioxide hauv kev tshaj tawm.
Peb xav tsis thoob tias cov kws tshawb fawb tau tsis quav ntsej txog cov xwm txheej ib puag ncig uas tswj hwm lub cev muaj feem cuam tshuam thaum lub sijhawm tag nrho cov txheej txheem ntawm tes kab lis kev cai, xws li kab lis kev cai acidity, txawm hais tias nws paub zoo tias qhov no tseem ceeb rau kev ua haujlwm ntawm tes.”
Pab neeg no yog coj los ntawm Carlos Duarte, tus kws tshawb fawb hauv dej hiav txwv ntawm KAUST, thiab Mo Li, tus kws paub txog kab mob hlwb, koom tes nrog Juan Carlos Izpisua Belmonte, tus kws kho tsiaj loj hlob ntawm Salk Institute.Tam sim no nws yog tus kws tshaj lij tuaj xyuas ntawm KAUST thiab pom zoo kom cov kws tshawb fawb biomedical tsim cov ntawv tshaj tawm thiab tswj thiab ntsuas cov txheej txheem, ntxiv rau kev siv cov cuab yeej tshwj xeeb los tswj kab lis kev cai ib puag ncig ntawm ntau hom cell.Cov ntawv xov xwm tshawb fawb yuav tsum tsim cov qauv kev tshaj tawm thiab xav tau kev saib xyuas kom txaus thiab tswj cov kua qaub ntawm cov xov xwm, cov pa oxygen thiab cov pa roj carbon dioxide.
"Kev tshaj tawm zoo dua, ntsuas, thiab tswj hwm thaj chaw ib puag ncig ntawm kab lis kev cai ntawm tes yuav tsum txhim kho lub peev xwm ntawm cov kws tshawb fawb rov ua dua thiab tsim cov txiaj ntsig kev sim tshiab," said Alsolami."Kev saib ze dua tuaj yeem tsav qhov kev tshawb pom tshiab thiab nce qhov cuam tshuam ntawm kev tshawb fawb ua ntej rau tib neeg lub cev."
"Mammalian kab lis kev cai ntawm tes yog lub hauv paus rau kev tsim cov tshuaj tiv thaiv kab mob thiab lwm yam biotechnologies," piav qhia tus kws tshawb fawb marine Shannon Klein."Ua ntej kev sim rau tsiaj thiab tib neeg, lawv tau siv los kawm txog cov kab mob hauv cell biology, rov ua cov txheej txheem kab mob, thiab kawm txog cov tshuaj lom ntawm cov tshuaj tshiab."
Klein, SG, thiab lwm yam. (2021) Kev tsis saib xyuas ib puag ncig ntawm kev tswj hwm ib puag ncig hauv kev coj noj coj ua ntawm tes yuav tsum muaj kev coj ua zoo tshaj.Natural Biomedical Engineering.doi.org/10.1038/s41551-021-00775-0.
Tags: B cell, cell, kab lis kev cai, incubator, mammalian cell, manufacturing, oxygen, pH, physiology, preclinical, tshawb fawb, T cell
Hauv kev xam phaj no, xibfwb John Rossen tau tham txog kev sib txuas ntawm cov tiam tom ntej thiab nws qhov cuam tshuam rau kev kuaj mob.
Hauv kev xam phaj no, Xov Xwm-Kev Kho Mob tau tham nrog xibfwb Dana Crawford txog nws txoj haujlwm tshawb fawb thaum lub sijhawm COVID-19 kis thoob qhov txhia chaw.
Hauv kev xam phaj no, Xov Xwm-Kev Kho Mob tau tham nrog Dr. Neeraj Narula txog cov khoom noj uas tau ua tiav thiab yuav ua li cas qhov no tuaj yeem ua rau koj muaj kev pheej hmoo ntawm kev mob plab hnyuv (IBD).
Xov Xwm-Medical.Net muab cov ntaub ntawv kho mob no ua raws li cov lus qhia thiab cov xwm txheej no.Thov nco ntsoov tias cov ntaub ntawv kho mob ntawm lub vev xaib no yog tsim los txhawb ntau dua li hloov kev sib raug zoo ntawm cov neeg mob thiab kws kho mob / kws kho mob thiab cov lus qhia kho mob uas lawv tuaj yeem muab.
Post lub sij hawm: Sep-07-2021
